BDBM197262 US9090621, 162A::US9572811, Example 162A

SMILES CC(C)(C=C(C#N)C(=O)N1CCC[C@H](C1)n1nc(-c2ccc(Oc3cccc(F)c3F)cc2F)c2c(N)ncnc12)N1CCOCC1

InChI Key InChIKey=NMPVOGJLOPRRNR-OAQYLSRUSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 197262   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM197262(US9090621, 162A | US9572811, Example 162A)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Principia Biopharma

US Patent
LigandPNGBDBM197262(US9090621, 162A | US9572811, Example 162A)
Affinity DataIC50:  0.900nMT: 2°CAssay Description:A Caliper-based kinase assay (Caliper Life Sciences, Hopkinton, Mass.) was used to measure inhibition of Btk kinase activity of a compound of Formula...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent