BDBM19759 benzyl N-[(1S)-1-{[(1R)-2-(benzyloxy)-1-cyanoethyl]carbamoyl}-3-methylbutyl]carbamate::dipeptidyl nitrile, 5h

SMILES CC(C)C[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](COCc1ccccc1)C#N

InChI Key InChIKey=BMFYRFFIWZYPGT-YADHBBJMSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19759   

TargetCathepsin K(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM19759(benzyl N-[(1S)-1-{[(1R)-2-(benzyloxy)-1-cyanoethyl...)
Affinity DataIC50:  9nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin S(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM19759(benzyl N-[(1S)-1-{[(1R)-2-(benzyloxy)-1-cyanoethyl...)
Affinity DataIC50:  969nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Novartis Pharmaceuticals

LigandPNGBDBM19759(benzyl N-[(1S)-1-{[(1R)-2-(benzyloxy)-1-cyanoethyl...)
Affinity DataIC50:  1.70E+3nMpH: 5.5 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed