BDBM20176 (1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6-methylheptan-2-yl]-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-7-en-5-ol::22(R)-hydroxycholesterol::22(S)-hydroxycholesterol

SMILES [H][C@](O)(CCC(C)C)[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])CC=C4C[C@@]([H])(O)CC[C@]4(C)[C@@]3([H])CC[C@]12C

InChI Key InChIKey=RZPAXNJLEKLXNO-UHFFFAOYSA-N

Data  4 KI  1 EC50  1 Other

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 20176   

TargetOxysterols receptor LXR-alpha(Human)
Dartmouth College

LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DataKi:  250nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
Eli Lilly

Curated by PDSP Ki Database
LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DataKi:  490nMMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetOxysterol-binding protein 2(Human)
University of Oklahoma

Curated by ChEMBL
LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DataKi: >3.00E+3nMAssay Description:Displacement of [3H]-25-OHC from human ORP4 overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetOxysterol-binding protein 1(Homo sapiens)
University of Oklahoma

Curated by ChEMBL
LigandPNGBDBM20176((1S,2R,5S,10S,11S,14R,15S)-14-[(2S,3S)-3-hydroxy-6...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]-25-OHC from human OSBP overexpressed in HEK293T cell lysate assessed as inhibition constant by competitive binding assayMore data for this Ligand-Target Pair
In DepthDetails
PubMed