BDBM203253 US9242970, 436

SMILES CCOc1cccc(Cl)c1[C@@H]1C[C@H](F)C(=O)N1Cc1ccc(OC(F)(F)F)cc1


Data  2 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 203253   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Actelion Pharmaceuticals Ltd

US Patent
LigandPNGBDBM203253(US9242970, 436)
Show SMILES CCOc1cccc(Cl)c1[C@@H]1C[C@H](F)C(=O)N1Cc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C20H18ClF4NO3/c1-2-28-17-5-3-4-14(21)18(17)16-10-15(22)19(27)26(16)11-12-6-8-13(9-7-12)29-20(23,24)25/h3-9,15-16H,2,10-11H2,1H3/t15-,16-/m0/s1
Affinity DataIC50: 965nMT: 2°CAssay Description:In Vitro Assay: Intracellular Calcium Measurements:Chinese hamster ovary (CHO) cells expressing the human orexin-1 receptor and the human orexin-2 re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid