BDBM207624 US10501467, Example 69::US9260440, 69::US9617273, Example 69

SMILES C[C@]12CCCN1Cc1n[nH]c(=O)c3cc(F)cc4[nH]c2c1c34

InChI Key InChIKey=HNHYFXQIDONXEC-MRXNPFEDSA-N

Data  33 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 207624   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
Affinity DataEC50:  13nMAssay Description:Inhibition of human PARP-1 catalytic domain (662 to 1011 residues) expressed in Escherichia coli BL21(DE3) cells incubated for 0.5 hrs by fluorescenc...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Beigene

US Patent
LigandPNGBDBM207624(US10501467, Example 69 | US9260440, 69 | US9617273...)
Affinity DataEC50:  0.200nMAssay Description:Inhibition of PARP-1 in human HeLa cells incubated for 18 hrs in presence of H2O2More data for this Ligand-Target Pair