BDBM21090 3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-methylphenyl)urea::Aminobenzoisoxazole, 33

SMILES Cc1ccc(NC(=O)Nc2ccc(cc2)-c2cccc3onc(N)c23)cc1

InChI Key InChIKey=DLYHIJZSZUMFEL-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 21090   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21090(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-met...)
Affinity DataIC50:  5nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21090(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-met...)
Affinity DataIC50:  16nM EC50:  44nMpH: 7.5 T: 2°CAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21090(3-[4-(3-amino-1,2-benzoxazol-4-yl)phenyl]-1-(4-met...)
Affinity DataIC50:  4nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed