BDBM21103 3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl]-1-(2-fluoro-5-methylphenyl)urea::Aminobenzoisoxazole, 49

SMILES COc1ccc(-c2ccc(NC(=O)Nc3cc(C)ccc3F)cc2)c2c(N)noc12

InChI Key InChIKey=SWNPCLQLHUWVAZ-UHFFFAOYSA-N

Data  7 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 21103   

TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  43nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAromatase(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  36nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  24nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  21nM EC50:  20nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  96nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiopoietin-1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  249nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM21103(3-[4-(3-amino-7-methoxy-1,2-benzoxazol-4-yl)phenyl...)
Affinity DataIC50:  27nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed