BDBM21605 2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-dihydrospiro[indole-3,3'-pyrrolidine]-2,2',5'-trione]acetic acid::Spiro-indolinone analogue, (R)-60

SMILES OC(=O)CN1C(=O)[C@@]2(CC(=O)N(Cc3cccc(Cl)c3)C2=O)c2cc(Cl)ccc12

InChI Key InChIKey=PTGHDUZXAIHWGN-HXUWFJFHSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 21605   

TargetProstaglandin D2 receptor 2(Homo sapiens (Human))
Merck Serono

LigandPNGBDBM21605(2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-d...)
Affinity DataKi:  23nM EC50:  107nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin D2 receptor 2(Mus musculus (mouse))
Merck Serono

LigandPNGBDBM21605(2-[(3R)-5-chloro-1'-[(3-chlorophenyl)methyl]-1,2-d...)
Affinity DataKi:  33nMAssay Description:A scintillation proximity assay was used for radioligand competition and saturation binding assays. Nonspecific binding was determined in the presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed