BDBM22111 (2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methylsulfanyl)methyl]oxolane-3,4-diol::(2R,3R,4S,5S)-2-(6-aminopurin-9-yl)-5-(methylsulfanylmethyl)oxolane-3,4-diol::5'-Methylthioado::5-methylthioadenosine::CHEMBL277041::MTA

SMILES CSC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2c(N)ncnc12

InChI Key InChIKey=WUUGFSXJNOTRMR-IOSLPCCCSA-N

Data  13 KI  4 IC50  1 Kd

PDB links: 98 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 22111   

TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methyl...)
Affinity DataIC50:  1.51E+4nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes with GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSpermidine synthase(Plasmodium falciparum)
Inovacia

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methyl...)
Affinity DataIC50:  1.59E+5nMAssay Description:Inhibition of Plasmodium falciparum spermidine synthaseMore data for this Ligand-Target Pair
TargetAdenosine receptor A1(Rattus norvegicus (rat))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methyl...)
Affinity DataIC50:  680nMAssay Description:Displacement of [3H]DPCPX from adenosine A1 receptor of rat cortical membranes without GTPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine receptor A3(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM22111((2R,3R,4S,5S)-2-(6-amino-9H-purin-9-yl)-5-[(methyl...)
Affinity DataIC50:  7.10E+4nMAssay Description:Inhibition of forskolin-stimulated cAMP accumulation in chinese hamster ovary cell membranes expressing human adenosine A3 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed