BDBM221955 US9303035, 1.23

SMILES Cn1c2c3C(NCCn3c(-c3ccccc3)c2c(=O)n(C)c1=O)c1ccc(Cl)cc1

InChI Key InChIKey=MLQXMVRMTRKLQN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 221955   

TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis

US Patent
LigandPNGBDBM221955(US9303035, 1.23)
Affinity DataIC50:  29.9nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent