BDBM221983 US9303035, 6.1
SMILES Cn1c2c3[C@@H](O[C@@H](CO)Cn3c(-c3cccc(c3)C#N)c2c(=O)n(C)c1=O)c1ccc(Cl)o1
InChI Key InChIKey=NRQUXFXWCYHFAG-SZNDQCEHSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 221983
TargetCystic fibrosis transmembrane conductance regulator(Cricetulus griseus (Chinese hamster))
Novartis
US Patent
Novartis
US Patent
Affinity DataIC50: 0.240nMAssay Description:CFTR activity can be quantified by electrophysiology methods, using the whole-cell configuration of the patch clamp technique (Hamill O, Marty A, Neh...More data for this Ligand-Target Pair