BDBM225230 EED226::US11013745, Compound EED226

SMILES CS(=O)(=O)c1ccc(cc1)-c1cnc(NCc2ccco2)n2cnnc12

InChI Key InChIKey=DYIRSNMPIZZNBK-UHFFFAOYSA-N

Data  87 IC50  3 Kd

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 225230   

TargetPolycomb protein EED(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  23nMAssay Description:Binding affinity to EED in PRC2 complex (unknown origin) using H3K27me0 (21 to 44 residue) peptide as substrate by LC-MS analysisMore data for this Ligand-Target Pair
TargetPolycomb protein EED(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataIC50:  45nMAssay Description:Displacement of UNC5114-biotin tracer ligand from N-terminal 6His-tagged EED (1 to 441 residues) (unknown origin) expressed in Escherichia coli Roset...More data for this Ligand-Target Pair