BDBM22720 2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluorophenyl)methyl]-5,6-dihydroxypyrimidine-4-carboxamide::CHEMBL386515::Dihydroxypyrimidine, 13

SMILES CN(C)C(C)(C)c1nc(C(=O)NCc2ccc(F)cc2)c(O)c(=O)[nH]1

InChI Key InChIKey=IQEPRBDBRZZHBI-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 22720   

TargetGag-Pol polyprotein(Human immunodeficiency virus type 1 group M subtyp...)
Irbm-Mrl

LigandPNGBDBM22720(2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluoropheny...)
Affinity DataIC50:  50nMpH: 7.8 T: 2°CAssay Description:The microtiter plate assay for stand transfer was performed with an immobilized donor substrate and a target substrate biotinylated at the 3-prime en...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM22720(2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluoropheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM22720(2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluoropheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM22720(2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluoropheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP1A2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM22720(2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluoropheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
P. Angeletti S.P.A. (Merck Research Laboratories)

Curated by ChEMBL
LigandPNGBDBM22720(2-[2-(dimethylamino)propan-2-yl]-N-[(4-fluoropheny...)
Affinity DataIC50: >2.00E+4nMAssay Description:Inhibition of CYP2C19More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed