BDBM22988 (5Z,8Z,11Z,14Z)-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide::AEA::ANANDAMIDE::Arachidonoyl ethanolamide::Arachidonoyl ethanolamide (AEA)::Arachidonoylethanolamide (AEA)::Arachidonylethanolamide::CHEMBL15848::[14C]Anandamide::[3H]Anandamide
SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCCO
InChI Key InChIKey=LGEQQWMQCRIYKG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 90 hits for monomerid = 22988
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of FAAH (unknown origin)More data for this Ligand-Target Pair
TargetPotassium two pore domain channel subfamily K member 2(Bovine)
University of Clermont Auvergne
Curated by ChEMBL
University of Clermont Auvergne
Curated by ChEMBL
Affinity DataIC50: 1.00E+3nMAssay Description:Activation of bovine TREK1 expressed in AZT cells assessed as reduction in channel currentsMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 16nMAssay Description:Agonist activity at TRPV1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of FAAHMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 490nMAssay Description:Agonist activity on human recombinant TRPV1-mediated enhancement of intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human CYP51 expressed in Topp 3 cells by lanosterol demethylase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+4nMAssay Description:Cannabinoid receptor 1 dependent activity of compound was evaluated by using [35S]GTP-gamma-S-binding studiesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of rat recombinant FAAH-mediated hydrolysis of [3H]AEAMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+4nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain membraneMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 630nMAssay Description:Activation of human VR1 expressed in HEK293 cells assessed as stimulation of Ca2+ influxMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with rat brain membrane in the presence of P...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rat)
National Research Council (Cnr)
Curated by ChEMBL
National Research Council (Cnr)
Curated by ChEMBL
Affinity DataIC50: 960nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
Affinity DataKd: 100nMAssay Description:The method entails two steps [Lin et al., Biochemistry, 38:185-190]. In the first step, the Kd for association of FABP5 with the fluorescent lipid pr...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rat)
National Research Council (Cnr)
Curated by ChEMBL
National Research Council (Cnr)
Curated by ChEMBL
Affinity DataIC50: 8.60E+3nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 200nMAssay Description:The effect of the substances on Ca2+ influx was determined by using HEK-293 cells stably overexpressing recombinant human TRPV1 cDNA. The cells were ...More data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human TASK1 expressed in African green monkey COS7 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
Affinity DataEC50: 69nMAssay Description:Agonist activity at rat CB1 receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 1.58E+4nMAssay Description:Displacement of [35S]GTP-gamma-S from rat cerebellar CB1 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Binding affinity towards Cannabinoid receptor 1 was determined using [3H]-CP- cannabinoid as radioligand with mouse brain membrane in the presence of...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -11.0kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 22nMAssay Description:Displacement of [3H]CP-55940 binding to Cannabinoid receptor 1 in rat brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 25nMAssay Description:Binding affinity towards cannabinoid receptor using [3H]CP-55940 as radioligand in rat brain membraneMore data for this Ligand-Target Pair
TargetCB1 cannabinoid receptor-interacting protein 1(Duck leech)
State University of New York At Old Westbury
Curated by PDSP Ki Database
State University of New York At Old Westbury
Curated by PDSP Ki Database
TargetCannabinoid receptor 1(Medicinal leech)
State University of New York At Old Westbury
Curated by PDSP Ki Database
State University of New York At Old Westbury
Curated by PDSP Ki Database
Affinity DataKi: 39nMAssay Description:In vitro binding affinity was determined against rat brain Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 39.2nMAssay Description:Compound was evaluated for its binding affinity towards Cannabinoid receptor 1 [Inactive form(R) of CB1 receptor]More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity for human cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 50nMAssay Description:Binding affinity to CB1R (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 52nMAssay Description:Ability to displace [3H]HU-243 binding to cannabinoid receptor in synaptosomal membraneMore data for this Ligand-Target Pair
Affinity DataKi: 61nMAssay Description:Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H...More data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP-55-940 from human recombinant CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Binding affinity to human recombinant CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP55940 from human CB1 receptor expressed in human HEK293 cells in presence of 100 nM PMSFMore data for this Ligand-Target Pair
Affinity DataKi: 70nMAssay Description:Displacement of [3H]CP-55-940 from human recombinant CB1 receptor in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptorMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Inhibition of [3H]CP-55940 binding to rat cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptor expressed in HEK cellsMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]-CP55940 from human recombinant CB1 receptor expressed in HEK cell membraneMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Binding affinity to human recombinant CB1 receptor expressed in african green monkey COS cells by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 72nMAssay Description:Displacement of [3H]CP-55,940 from human recombinant CB1 receptor expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
Affinity DataKi: 74nMAssay Description:Displacement of [3H]CP-55,940 from CB1 receptor in rat brain membranes in presence of FAAH inhibitor PMSF by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Displacement of [3H]CP-55940 from Cannabinoid receptor 1 of rat forebrain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Binding affinity for the cannabinoid receptor in the presence of phenylmethanesulfonyl fluoride (PMSF) was determined in rat fore brain membranesMore data for this Ligand-Target Pair
Affinity DataKi: 78nMAssay Description:Tested for binding affinity to Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity to CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:The compound was tested for Ki value against rat whole brain P2 membrane preparation in presence of enzyme inhibitor PMSF.More data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity to human CB1 receptor in presence of serine protease inhibitor PMSFMore data for this Ligand-Target Pair
Affinity DataKi: 89nMAssay Description:Binding affinity towards cloned human Cannabinoid receptor 1More data for this Ligand-Target Pair