BDBM23402 5-(1,1-dioxo-1,2-thiazinan-2-yl)-N-[(4-fluorophenyl)methyl]-8-hydroxy-1,6-naphthyridine-7-carboxamide::CHEMBL414850::L-870,810
SMILES Oc1c(nc(N2CCCCS2(=O)=O)c2cccnc12)C(=O)NCc1ccc(F)cc1
InChI Key InChIKey=DIDKWCOCQJWMDJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 10 hits for monomerid = 23402
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataKi: 7.30E+3nMAssay Description:Displacement of [125I]adrenomedullin form CGRP receptor in human SK-N-MC cell membrane by competitive binding assayMore data for this Ligand-Target Pair
Affinity DataIC50: 13nMpH: 7.2 T: 2°CAssay Description:Purified recombinant integrase was first combined in a complex with biotinylated donor DNA- streptavidin-coated SPA beads. The complex was preincubat...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of strand transfer activity of HIV integraseMore data for this Ligand-Target Pair
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant HIV1 integrase strand transfer activityMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:In vitro concentration required to inhibit the overall HIV-1 integrase strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase strand transferMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Strand transfer inhibitory activity against HIV-1 integraseMore data for this Ligand-Target Pair
TargetCalcitonin gene-related peptide 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of CGRP receptor in human SK-N-MC cells assessed as inhibition of CGRP-stimulated cAMP production after 1 hrMore data for this Ligand-Target Pair
Affinity DataIC50: 44nMpH: 7.3 T: 2°CAssay Description:In the 3-end joining assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow process...More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:In vitro concentration required to inhibit the HIV-1 integrase 3' strand transferMore data for this Ligand-Target Pair