BDBM382 1571-30-8::55088_ALDRICH::8-hydroxy-2-quinolinecarboxylic acid::8-hydroxyquinaldic acid::8-hydroxyquinoline-2-carboxylic acid::8-oxidanylquinoline-2-carboxylic acid::BDBM237136::BRN 0146082::MLS000849721::Oprea1_440614::Quinaldic acid, 8-hydroxy-::ST086494::cid_74079

SMILES OC(=O)c1ccc2cccc(O)c2n1

InChI Key InChIKey=UHBIKXOBLZWFKM-UHFFFAOYSA-N

Data  3 IC50  1 Kd  1 EC50  1 ITC

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 382   

TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain H37Rv))
The University Of Denver And Regis University

US Patent
LigandPNGBDBM382(1571-30-8 | 55088_ALDRICH | 8-hydroxy-2-quinolinec...)
Affinity DataIC50:  1.70E+4nM Kd:  6.94E+3nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetFructose-bisphosphate aldolase(Mycobacterium tuberculosis (strain H37Rv))
The University Of Denver And Regis University

US Patent
LigandPNGBDBM382(1571-30-8 | 55088_ALDRICH | 8-hydroxy-2-quinolinec...)
Affinity DataIC50:  1.40E+4nMAssay Description:Enzymatic activity is measured by contacting the enzyme with a suitable substrate, such as fructose 1,6-bisphosphate, and measuring formation of a pr...More data for this Ligand-Target Pair
In DepthDetails US Patent

Activity Spreadsheet -- ITC Data from BindingDB

Found 1 hit for monomerid = 382   

CellFructose-1,6-bisphosphate aldolase (FBA)(Mycobacterium tuberculosis (strain H37Rv))
The University Of Denver And Regis University

US Patent
SyringePNGBDBM382(1571-30-8 | 55088_ALDRICH | 8-hydroxy-2-quinolinec...)
ITC DataΔH°: -6.86kcal/mole
In DepthDetails US Patent