BDBM237300 4-Methyl-N-o-tolyl-benzenesulfonamide (5)

SMILES Cc1ccc(cc1)S(=O)(=O)Nc1ccccc1C

InChI Key InChIKey=SIPGNSRRMHEOSA-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 237300   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataKi:  386nM ΔG°:  -8.74kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataKi:  615nM ΔG°:  -8.47kcal/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50:  407nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50:  1.48E+5nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 6(Homo sapiens (Human))
Ataturk University

LigandPNGBDBM237300(4-Methyl-N-o-tolyl-benzenesulfonamide (5))
Affinity DataIC50:  2.96E+4nMAssay Description:Carbonic anhydrase activity was assayed by following the change in absorbance at 348 nm of 4-nitrophenylacetate (NPA) to 4-nitrophenylate ion over a ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed