BDBM24182 4-amino-3-(4-chlorophenyl)butanoic acid::Baclofen::Baclophen::CHEMBL701::Gabalon::Lioresal

SMILES NCC(CC(O)=O)c1ccc(Cl)cc1

InChI Key InChIKey=KPYSYYIEGFHWSV-UHFFFAOYSA-N

Data  2 KI  14 IC50  2 EC50

PDB links: 3 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 24182   

TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]CGP54626 from GABA-B receptor (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
TargetGamma-aminobutyric acid type B receptor subunit 1/2(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM24182(4-amino-3-(4-chlorophenyl)butanoic acid | Baclofen...)
Affinity DataEC50:  1.70E+3nMAssay Description:Agonist activity at human GABA-B B1/B2 receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation after 3 hr...More data for this Ligand-Target Pair