BDBM246487 Batatasin III (4)

SMILES COc1cc(O)cc(CCc2cccc(O)c2)c1

InChI Key InChIKey=VYQXIUVIYICVCM-UHFFFAOYSA-N

Data  1 KI  3 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 246487   

TargetPancreatic triacylglycerol lipase(Sus scrofa (Pig))
Seoul National University

LigandPNGBDBM246487(Batatasin III (4))
Affinity DataKi:  6.79E+3nM ΔG°:  -7.33kcal/mole IC50:  3.23E+4nMpH: 7.4 T: 2°CAssay Description:Various concentrations of test compound (5, 10, 25, 50 and 100 mM) were dissolved in DMSO (final culture concentration 0.1%) and 4-MU oleate and lipa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4))
Affinity DataIC50: >4.09E+5nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-2/beta-2/gamma-2(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4))
Affinity DataEC50:  8.08E+4nMAssay Description:Modulation of GABAA alpha2beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4))
Affinity DataIC50: >4.09E+5nMAssay Description:Inhibition of ovine COX1 by colorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4))
Affinity DataEC50:  6.72E+4nMAssay Description:Modulation of GABAA alpha1beta3gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
Target InfoGoogleScholar
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-2/gamma-2(Homo sapiens (Human))
University Of Basel

Curated by ChEMBL
LigandPNGBDBM246487(Batatasin III (4))
Affinity DataEC50:  6.73E+4nMAssay Description:Modulation of GABAA alpha3beta2gamma2S receptor (unknown origin) expressed in Xenopus laevis oocytes assessed as potentiation of EC3 to 10 GABA-induc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed