BDBM246524 Psoralidin (5)

SMILES [#6]\[#6](-[#6])=[#6]\[#6]-c1cc2c3oc4cc(-[#8])ccc4c3c(=O)oc2cc1-[#8]

InChI Key InChIKey=YABIJLLNNFURIJ-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 246524   

TargetReplicase polyprotein 1a(Human SARS coronavirus (SARS-CoV))
Gyeongsang National University

LigandPNGBDBM246524(Psoralidin (5))
Affinity DataKi:  1.70E+3nM IC50:  4.20E+3nMpH: 8.0Assay Description:Reactions were performed in a total volume of 200 mL, which contained thefollowing components: 20mM Tris-buffer, pH 8.0, 10mM DTT, 30 mM Z-RLRGG-AMC,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetReplicase polyprotein 1a/Z-RLRGG-AMC(Human SARS coronavirus (SARS-CoV))
Gyeongsang National University

LigandPNGBDBM246524(Psoralidin (5))
Affinity DataKi:  4.20E+3nMpH: 8.0Assay Description:Reactions were performed in a total volume of 200 mL, which contained thefollowing components: 20mM Tris-buffer, pH 8.0, 10mM DTT, 30 mM Z-RLRGG-AMC,...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Goethe-University Frankfurt

Curated by ChEMBL
LigandPNGBDBM246524(Psoralidin (5))
Affinity DataKd:  2.10E+4nMAssay Description:Binding affinity to recombinant human 6His-tagged FLAP expressed in Escherichia coli BL21 (DE3) by isothermal titration calorimetric methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed