BDBM246573 2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]acetyl}-benzenesulfonamide (2j)

SMILES CSc1nc2ccccc2n1CC(=O)c1ccc(c(Cl)c1)S(N)(=O)=O

InChI Key InChIKey=KTFHRLLBPKIZGX-UHFFFAOYSA-N

Data  5 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 246573   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM246573(2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]a...)
Affinity DataKd:  1.67nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM246573(2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]a...)
Affinity DataKd:  3.33nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 13(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM246573(2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]a...)
Affinity DataKd:  9.09nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 12(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM246573(2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]a...)
Affinity DataKd:  66.7nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 7(Homo sapiens (Human))
Vilnius University

LigandPNGBDBM246573(2-Chloro-4-{[2-(methylthio)-1H-benzimidazol-1-yl]a...)
Affinity DataKd:  4.54nMpH: 7.0Assay Description:The thermal shift assay (TSA) measurements were performed in a Corbett Rotor-Gene 6000 (QIAGEN Rotor-Gene Q, Sydney, Australia) instrument using the ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed