BDBM24978 (3R,4R)-1-(benzyloxy)-3-hexyl-4-[(2R)-2-hydroxytridecyl]azetidin-2-one::beta-lactam derivative of orlistat, (+)-10

SMILES CCCCCCCCCCC[C@@H](O)C[C@@H]1[C@@H](CCCCCC)C(=O)N1OCc1ccccc1

InChI Key InChIKey=MIMIBHJFIRJLRW-JCYYIGJDSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 24978   

TargetFatty acid synthase [2202-2509](Homo sapiens (Human))
Texas A&M University

LigandPNGBDBM24978((3R,4R)-1-(benzyloxy)-3-hexyl-4-[(2R)-2-hydroxytri...)
Affinity DataIC50:  6.12E+4nMpH: 7.4 T: 2°CAssay Description:The reaction mixture consisted of FAS thioesterase domain (FASTE) in buffer, which was preincubated with test compounds for 30 min. The reaction was ...More data for this Ligand-Target Pair
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