BDBM25392 4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;hydrochloride::4-[1-hydroxy-2-(propan-2-ylamino)ethyl]benzene-1,2-diol::4-{1-hydroxy-2-[(propan-2-yl)amino]ethyl}benzene-1,2-diol, 2::CHEMBL434::ISOPROTERONOL::Isoprenaline::Isoproterenol::Isoproterenol (-)::Isoproterenol,(+)::Isoproterenol-l::Norisodrine::Novodrin

SMILES CC(C)NCC(O)c1ccc(O)c(O)c1

InChI Key InChIKey=JWZZKOKVBUJMES-UHFFFAOYSA-N

Data  39 KI  12 IC50  11 Kd  89 EC50

PDB links: 9 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 25392   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataKi:  501nMAssay Description:Displacement of [3H]-DHA from recombinant human beta2 adrenoceptor expressed in HEK293T cellsMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataEC50:  240nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in HEK293T cells assessed as increase in IBMX-induced cAMP accumulation using [3H]...More data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataEC50:  129nMAssay Description:Agonist activity at recombinant human beta2 adrenoceptor expressed in DU145 cells assessed as increase in cAMP accumulationMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataKd:  50nMAssay Description:Binding affinity to human adrenergic beta2 receptorMore data for this Ligand-Target Pair
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataKd:  18nMAssay Description:Agonist activity at adrenergic beta2 receptor in Hartley guinea pig tracheal ring assessed as bronchorelaxation activity against histamine-induced co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-2 adrenergic receptor(GUINEA PIG)
Instituto Polit£Cnico Nacional (Ipn)

Curated by ChEMBL
LigandPNGBDBM25392(4-[1-hydroxy-2-(isopropylamino)ethyl]pyrocatechol;...)
Affinity DataKd:  25nMAssay Description:Agonist activity at adrenergic beta2 receptor in Hartley guinea pig tracheal ring at basal tone assessed as bronchorelaxation activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed