BDBM25752 Betaxolol::Levobetaxolol::[(2S)-3-{4-[2-(cyclopropylmethoxy)ethyl]phenoxy}-2-hydroxypropyl](propan-2-yl)amine

SMILES CC(C)NC[C@H](O)COc1ccc(CCOCC2CC2)cc1

InChI Key InChIKey=NWIUTZDMDHAVTP-KRWDZBQOSA-N

Data  3 KI  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25752   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

LigandPNGBDBM25752(Betaxolol | Levobetaxolol | [(2S)-3-{4-[2-(cyclopr...)
Affinity DataKd:  42nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

LigandPNGBDBM25752(Betaxolol | Levobetaxolol | [(2S)-3-{4-[2-(cyclopr...)
Affinity DataKd:  6.20nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

LigandPNGBDBM25752(Betaxolol | Levobetaxolol | [(2S)-3-{4-[2-(cyclopr...)
Affinity DataKd:  1.07E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed