BDBM25762 CHEMBL471::N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide::SOTALOL HYDROCHLORIDE::Sotalol::Sotalol,(+)::Sotalol,(-)::cid_66245

SMILES CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N

Data  6 KI  15 IC50  5 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 25762   

TargetBeta-3 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataKd:  8.91E+3nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataKd:  1.70E+3nMpH: 7.4 T: 2°CAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
University Of Nottingham

LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataKd:  141nMAssay Description:The whole cell-binding studies were undertaken in CHO cell lines stably expressing each beta-adrenoceptor subtype. Nonspecific binding was determined...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank