BDBM25762 CHEMBL471::N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide::SOTALOL HYDROCHLORIDE::Sotalol::Sotalol,(+)::Sotalol,(-)::cid_66245

SMILES CC(C)NCC(O)c1ccc(NS(C)(=O)=O)cc1

InChI Key InChIKey=ZBMZVLHSJCTVON-UHFFFAOYSA-N

Data  6 KI  15 IC50  5 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 25762   

TargetBeta-2 adrenergic receptor(Canis familiaris)
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataIC50:  5.00E+3nMAssay Description:Binding affinity towards Beta-2 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine lung ti...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-1 adrenergic receptor(Homo sapiens (Human))
Berlex Laboratories

Curated by ChEMBL
LigandPNGBDBM25762(CHEMBL471 | N-{4-[1-hydroxy-2-(propan-2-ylamino)et...)
Affinity DataIC50:  9.00E+3nMAssay Description:Binding affinity for Beta-1 adrenergic receptor by displacing [3H]dihydroalprenolol, in partially purified membrane fractions from canine ventricular...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedDrugBank