BDBM25873 8-{4-[2-methyl-4-(quinolin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione::buspirone analogue, 4
SMILES CC1CN(CCN1CCCCN1C(=O)CC2(CCCC2)CC1=O)c1ccc2ccccc2n1
InChI Key InChIKey=ZFBYBMSLWDHRKG-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 25873
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
National Medicines Institute
Curated by ChEMBL
National Medicines Institute
Curated by ChEMBL
Affinity DataKi: 24nMAssay Description:Displacement of [3H]8-OH-DPAT from 5HT1A receptor in cerebral cortex homogenates after 15 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 75nMpH: 7.7 T: 2°CAssay Description:Ligand binding experiments were conducted in assay tubes containing radioligand, membrane tissue, and test compounds. Incubations were terminated by ...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMAssay Description:Displacement of [3H]-Citalopram from SERT in rat cerebral cortex homogenates after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair