BDBM26132 (4-phenylphenyl)boranediol::Phenylboronic Acid, 11::Phenylboronic acid, 23

SMILES OB(O)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=XPEIJWZLPWNNOK-UHFFFAOYSA-N

Data  3 KI  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 26132   

TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataKi:  3.70E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 1 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universit£

Curated by ChEMBL
LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataKi:  4.50E+3nMAssay Description:Inhibition of human recombinant cytosolic carbonic anhydrase 2 preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCarbonic anhydrase(Candida albicans (Yeast))
Universit£

Curated by ChEMBL
LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of Candida albicans recombinant Carbonic anhydrase preincubated for 15 mins by CO2 hydration stopped-flow assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 2(Homo sapiens (Human))
Technical University Of Dortmund

LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50:  3.55E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at recombinant human TRPV1 channel expressed in HEK293 cells assessed as inhibition of capsiacin-induced Ca2+ flux preincubated f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-protein thioesterase 1(Homo sapiens (Human))
Technical University Of Dortmund

LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50:  1.69E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMonoglyceride lipase(Homo sapiens (Human))
University Of Oxford

LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50:  1.90E+4nMAssay Description:The endpoint enzymatic assay was developed to quantify human recombinant MGL activity with 2-AG. The formation of arachidonic acid and depletion of ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Oxford

LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50:  21nMpH: 7.4 T: 2°CAssay Description:[3H]Ethanolamine produced from [3H]AEA hydrolysis was used to calculate FAAH activity and was measured by scintillation counting of the aqueous phase...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rattus norvegicus (rat))
University Of Oxford

LigandPNGBDBM26132((4-phenylphenyl)boranediol | Phenylboronic Acid, 1...)
Affinity DataIC50:  790nMAssay Description:Inhibition of rat brain FAAH assessed as hydrolysis of [14C]AEA to [14C]Ethanolamine incubated for 30 mins by scintillation counting methodMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed