BDBM262403 Methyl 3-sulfamoyl-4-(2H-tetrazol-5-yl)benzoate::US9708336, 255

SMILES COC(=O)c1ccc(-c2nn[nH]n2)c(c1)S(N)(=O)=O

InChI Key InChIKey=IKHWRVYGFJFJJY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 262403   

TargetMetallo-beta-lactamase type 2(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 262403BDBM262403(US9708336, 255 | Methyl 3-sulfamoyl-4-(2H-tetrazol...)
Affinity DataIC50: 699nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetVIM-1 metallo-beta-lactamase(Pseudomonas aeruginosa (g-Proteobacteria))
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 262403BDBM262403(US9708336, 255 | Methyl 3-sulfamoyl-4-(2H-tetrazol...)
Affinity DataIC50: 2.00E+4nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent

TargetMetallo-beta-lactamase type 2(Serratia marcescens)
Merck Sharp & Dohme

US Patent
LigandChemical structure of BindingDB Monomer ID 262403BDBM262403(US9708336, 255 | Methyl 3-sulfamoyl-4-(2H-tetrazol...)
Affinity DataIC50: 2.00E+4nMpH: 7.0Assay Description:The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2018
Entry Details
US Patent