BDBM26646 (5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidine-2,4-dione::CHEMBL1814640::thiazolidine-2,4-dione, 24a
SMILES OC1=NC(=O)C(S1)=Cc1cccc(Br)c1
InChI Key InChIKey=ULWSONREDISANN-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 26646
TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University Of South Carolina
Medical University Of South Carolina
Affinity DataIC50: 4.50E+4nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University Of South Carolina
Medical University Of South Carolina
Affinity DataIC50: 100nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Northeastern Ohio Universities Colleges Of Medicine And Pharmacy
Curated by ChEMBL
Northeastern Ohio Universities Colleges Of Medicine And Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.07E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Northeastern Ohio Universities Colleges Of Medicine And Pharmacy
Curated by ChEMBL
Northeastern Ohio Universities Colleges Of Medicine And Pharmacy
Curated by ChEMBL
Affinity DataIC50: 6.73E+4nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
TargetCDGSH iron-sulfur domain-containing protein 1(Homo sapiens (Human))
Northeast Ohio Medical University
Curated by ChEMBL
Northeast Ohio Medical University
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair