BDBM26646 (5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidine-2,4-dione::CHEMBL1814640::thiazolidine-2,4-dione, 24a

SMILES OC1=NC(=O)C(S1)=Cc1cccc(Br)c1

InChI Key InChIKey=ULWSONREDISANN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 26646   

TargetSerine/threonine-protein kinase pim-1(Homo sapiens (Human))
Medical University Of South Carolina

LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  4.50E+4nMpH: 7.0 T: 2°CAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine/threonine-protein kinase pim-2(Homo sapiens (Human))
Medical University Of South Carolina

LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  100nMAssay Description:The primary screen and evaluation of the compounds was conducted using an ATP-depletion assay. Recombinant human Pim kinase was incubated with S6 kin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Northeastern Ohio Universities Colleges Of Medicine And Pharmacy

Curated by ChEMBL
LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  6.07E+3nMAssay Description:Inhibition of human recombinant MAOB by amplex red assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Northeastern Ohio Universities Colleges Of Medicine And Pharmacy

Curated by ChEMBL
LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  6.73E+4nMAssay Description:Inhibition of human recombinant MAOA assessed as inhibition of kynuramine conversion to fluorescent metabolite 4-hydroxyquinoline by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCDGSH iron-sulfur domain-containing protein 1(Homo sapiens (Human))
Northeast Ohio Medical University

Curated by ChEMBL
LigandPNGBDBM26646((5Z)-5-[(3-bromophenyl)methylidene]-1,3-thiazolidi...)
Affinity DataIC50:  860nMAssay Description:Displacement of [3H]-rosiglitazone from human recombinant C-terminal His-tagged cytosolic domain of mitoNEET (32-108) by scintillation proximity assa...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed