BDBM267033 Methyl 2-(acetyloxy)-4-{[(4,5-dichlorothiophen-2-yl)sulfonyl]amino}benzoate::US9718809, 132

SMILES COC(=O)c1ccc(NS(=O)(=O)c2cc(Cl)c(Cl)s2)cc1OC(C)=O

InChI Key InChIKey=HKTZGBDMIMBGPU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 267033   

Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM267033(Methyl 2-(acetyloxy)-4-{[(4,5-dichlorothiophen-2-y...)
Affinity DataIC50:  1.18E+4nMAssay Description:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
Target6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4(Homo sapiens (Human))
Kancera

US Patent
LigandPNGBDBM267033(Methyl 2-(acetyloxy)-4-{[(4,5-dichlorothiophen-2-y...)
Affinity DataIC50:  1.50E+3nMAssay Description:6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase (PFK-2/BPase-2) is a bi-functional enzyme that catalyses the formation and degradation of fructo...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent