BDBM27749 3-[(4-fluorophenyl)methyl]-9-hydroxy-5-methoxy-6H,7H,8H-pyrrolo[3,4-g]quinolin-8-one::tricyclic pyrroloquinoline, 9

SMILES COc1c2CNC(=O)c2c(O)c2ncc(Cc3ccc(F)cc3)cc12

InChI Key InChIKey=XRBIRQRZNGSARA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27749   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences Inc

LigandPNGBDBM27749(3-[(4-fluorophenyl)methyl]-9-hydroxy-5-methoxy-6H,...)
Affinity DataIC50:  14nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed