BDBM27751 N-{3-[(4-fluorophenyl)methyl]-9-hydroxy-7-methyl-8-oxo-6H,7H,8H-pyrrolo[3,4-g]quinolin-5-yl}-N-methylmethanesulfonamide::tricyclic pyrroloquinoline, 20

SMILES CN(c1c2CN(C)C(=O)c2c(O)c2ncc(Cc3ccc(F)cc3)cc12)S(C)(=O)=O

InChI Key InChIKey=ACGUPURFNDYXDD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 27751   

TargetGag-Pol polyprotein [1148-1435](Human immunodeficiency virus type 1)
Gilead Sciences

LigandPNGBDBM27751(N-{3-[(4-fluorophenyl)methyl]-9-hydroxy-7-methyl-8...)
Affinity DataIC50:  80nMpH: 7.3 T: 2°CAssay Description:In the strand-transfer assay, the biotinylated donor DNA was bound to streptavidin-coated plates, and integrase was added to each well to allow proce...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed