BDBM28088 3-cyanoquinoline, 13::4-({3-chloro-4-[(1,4,5-trimethyl-1H-imidazol-2-yl)sulfanyl]phenyl}amino)-7-{[3-(dimethylamino)propyl]amino}-6-methoxyquinoline-3-carbonitrile

SMILES COc1cc2c(Nc3ccc(Sc4nc(C)c(C)n4C)c(Cl)c3)c(cnc2cc1NCCCN(C)C)C#N

InChI Key InChIKey=ITBPEUZGPKJPRM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28088   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28088(3-cyanoquinoline, 13 | 4-({3-chloro-4-[(1,4,5-trim...)
Affinity DataIC50:  26nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed