BDBM28107 3-cyanoquinoline, 32::4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-2-yl)sulfanyl]phenyl}amino)-7-[3-(3-hydroxypyrrolidin-1-yl)propoxy]-6-methoxyquinoline-3-carbonitrile

SMILES CCn1c(C)c(C)nc1Sc1ccc(Nc2c(cnc3cc(OCCCN4CCC(O)C4)c(OC)cc23)C#N)cc1Cl

InChI Key InChIKey=KUCZEJMQMXTIAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 28107   

TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
Wyeth Research

LigandPNGBDBM28107(3-cyanoquinoline, 32 | 4-({3-chloro-4-[(1-ethyl-4,...)
Affinity DataIC50:  20nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed