BDBM284972 N-[2-methyl-5-(2-methyl-1-oxoiso- quinolin-4-yl)phenyl]methanesulfonamide::US10023592, Example 17

SMILES Cc1ccc(cc1NS(C)(=O)=O)-c1cn(C)c(=O)c2ccccc12

InChI Key InChIKey=CNDVAKVYDBVIAA-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 284972   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM284972(N-[2-methyl-5-(2-methyl-1-oxoiso- quinolin-4-yl)ph...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent