BDBM284982 N-benzyl-3-(2-methyl-1-oxoisoquinolin-4-yl) benzenesulfonamide::US10023592, Example 27
SMILES Cn1cc(-c2cccc(c2)S(=O)(=O)NCc2ccccc2)c2ccccc2c1=O
InChI Key InChIKey=GNWSRCGEQJSQOE-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 284982
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 2.99E+3nMAssay Description:Inhibition of His-tagged human BRD4-BD1 using H4K5acK8acK12acK16ac as substrate preincubated for 30 mins followed by substrate addition measured afte...More data for this Ligand-Target Pair
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research
Curated by ChEMBL
Celgene Quanticel Research
Curated by ChEMBL
Affinity DataIC50: 2.75E+3nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair