BDBM285282 1,3-dimethyl-5-[3-methylsulfonyl-5-(pyridin-2- ylmethoxy)phenyl]pyridin-2-one::BDBM486126::US10023592, Example 330

SMILES Cc1cc(cn(C)c1=O)-c1cc(OCc2ccccn2)cc(c1)S(C)(=O)=O

InChI Key InChIKey=LRZHIMAYJUNZNR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285282   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285282(1,3-dimethyl-5-[3-methylsulfonyl-5-(pyridin-2- ylm...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285282(1,3-dimethyl-5-[3-methylsulfonyl-5-(pyridin-2- ylm...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent