BDBM285294 N-[3-(2,4-difluorophenoxy)-5-(1,5-dimethyl- 6-oxopyridin-3-yl)phenyl]ethanesulfonamide::US10023592, Example 342

SMILES CCS(=O)(=O)Nc1cc(Oc2ccc(F)cc2F)cc(c1)-c1cc(C)c(=O)n(C)c1

InChI Key InChIKey=FMNWTIKNQGHQGB-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 285294   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285294(N-[3-(2,4-difluorophenoxy)-5-(1,5-dimethyl- 6-oxop...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent