BDBM285448 5-[2-(methoxymethyl)-7-methylsulfonyl-2,3- dihydro-1,4-benzodioxin-5-yl]-1,3- dimethylpyridin-2-one::BDBM486292::US10023592, Example 502

SMILES COCC1COc2c(O1)cc(cc2-c1cc(C)c(=O)n(C)c1)S(C)(=O)=O

InChI Key InChIKey=SCNPXLZDSJYAFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285448   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285448(5-[2-(methoxymethyl)-7-methylsulfonyl-2,3- dihydro...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285448(5-[2-(methoxymethyl)-7-methylsulfonyl-2,3- dihydro...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent