BDBM285457 N-[5-butyl-4-(5-methyl-6-oxo-1-propan-2- ylpyridin-3-yl)pyrimidin-2-yl] ethanesulfonamide::US10023592, Example 511::US10941160, Example 511

SMILES CCCCc1cnc(CC)nc1-c1cc(C)c(=O)n(c1)C(C)C

InChI Key InChIKey=XLZQVAZBBXJXRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 285457   

TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285457(N-[5-butyl-4-(5-methyl-6-oxo-1-propan-2- ylpyridin...)
Affinity DataIC50: <500nMAssay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBromodomain-containing protein 4(Homo sapiens (Human))
Celgene Quanticel Research

US Patent
LigandPNGBDBM285457(N-[5-butyl-4-(5-methyl-6-oxo-1-propan-2- ylpyridin...)
Affinity DataIC50: <500nMpH: 7.3Assay Description:Determination of the IC50 for the heterocyclic derivative BRD4 inhibitors disclosed herein was performed as follows. His-tagged BRD4 was cloned, expr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent