BDBM29000 (2R)-2-{[5-chloro-2-(hydroxymethyl)phenyl](4-chlorobenzene)sulfonamido}propyl pyrrolidine-1-carboxylate::Carbamate-appended N-alkylsulfonamide, 22
SMILES C[C@H](COC(=O)N1CCCC1)N(c1cc(Cl)ccc1CO)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=YJVWYJVIHWQADX-OAHLLOKOSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 29000
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataEC50: 1.80nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair