BDBM29011 (2R)-2-[(4-chlorobenzene)(2,5-dichlorophenyl)sulfonamido]propyl N-ethyl-N-[3-(1H-imidazol-1-yl)propyl]carbamate::Carbamate-appended N-alkylsulfonamide, 54
SMILES CCN(CCCn1ccnc1)C(=O)OC[C@@H](C)N(c1cc(Cl)ccc1Cl)S(=O)(=O)c1ccc(Cl)cc1
InChI Key InChIKey=DIKBTZFFACQGQU-GOSISDBHSA-N
Data 1 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 29011
TargetGamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1(Homo sapiens (Human))
Bristol-Myers Squibb
Bristol-Myers Squibb
Affinity DataEC50: 0.270nMAssay Description:H4 human neuroglioma cells expressing beta-APP were aliquoted into a 96-well plate, and after attachment the medium was replaced with the conditioned...More data for this Ligand-Target Pair