BDBM29080 CHEMBL280065::N-oleoylethanolamine::Oleamide MEA::Oleoyl monoethanolamide::Oleoylethanolamide (OEA)
SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NCCO
InChI Key InChIKey=BOWVQLFMWHZBEF-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 33 hits for monomerid = 29080
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 40nMAssay Description:Agonist activity at TRPV1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Activation of recombinant His-tagged SIRT6 (unknown origin) deacetylase activity expressed in Escherichia coli using H3K9Ac peptide substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Activation of human SIRT6 deacetylase activity expressed in Escherichia coli BL21(DE3) expressed in Escherichia coli using H3K9Ac peptide substrateMore data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Activation of his6-tagged SIRT6 (unknown origin) using H3K9Ac peptide substrate incubated for 30 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human acid ceramidaseMore data for this Ligand-Target Pair
Affinity DataEC50: 930nMAssay Description:Agonist activity at GPR119 (unknown origin) assessed as increase in cAMP level by cAMP HTRF assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor delta(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 1.10E+3nMAssay Description:Transactivation of human Gal4 fused PPARdelta LBD transfected in human HeLa cells after 7 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 120nMAssay Description:Transactivation of human Gal4 fused PPARalpha LBD transfected in human HeLa cells after 7 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rat)
National Research Council (Cnr)
Curated by ChEMBL
National Research Council (Cnr)
Curated by ChEMBL
Affinity DataIC50: 5.40E+3nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of CBD-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 2(Rat)
National Research Council (Cnr)
Curated by ChEMBL
National Research Council (Cnr)
Curated by ChEMBL
Affinity DataIC50: 1.80E+3nMAssay Description:Antagonist activity at recombinant rat TRPV2 expressed in HEK293 cells assessed as inhibition of LPC-induced Ca2+ levels preincubated for 5 mins foll...More data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at GPR119 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as increase in cAMP stimulation measured after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 185nMAssay Description:Agonist activity at human PPARalpha expressed in MCF7 cells co-transfected CPTI DR1-type RE after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 152nMAssay Description:Agonist activity at human PPARalpha expressed in MCF7 cells co-transfected CPTI DR1-type RE after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Agonist activity at human GPR119 transfected in HEK293 cells assessed as concentration for 50 % cAMP stimulation of oleylethanolamineMore data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as cAMP accumulation after 60 minsMore data for this Ligand-Target Pair
Affinity DataEC50: 3.20E+3nMAssay Description:Agonist activity at recombinant GPR119 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 2.20E+3nMAssay Description:Agonist activity at human GPR119 expressed in HEK293 cells assessed as stimulation of cAMP level measured after 60 mins by HTRF assayMore data for this Ligand-Target Pair
Affinity DataEC50: 2.90E+3nMAssay Description:Agonist activity at mouse GPR119 receptor cotransformed in Saccharomyces cerevisiae cells after 4 hrs by fluorescent Fus1p-LacZ reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 152nMAssay Description:Agonist activity at human PPARalpha transfected in human MCF7 cells after 16 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
TargetPeroxisome proliferator-activated receptor alpha(Human)
The University of Tokyo
Curated by ChEMBL
The University of Tokyo
Curated by ChEMBL
Affinity DataEC50: 110nMAssay Description:Activation of human PPARalpha by GST pull down assayMore data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 3.65E+3nMAssay Description:The effect of the substances on Ca2+ influx was determined by using HEK-293 cells stably overexpressing recombinant human TRPV1 cDNA. The cells were ...More data for this Ligand-Target Pair
TargetTransient receptor potential cation channel subfamily V member 1(Human)
Hebrew University of Jerusalem
Curated by ChEMBL
Hebrew University of Jerusalem
Curated by ChEMBL
Affinity DataEC50: 890nMAssay Description:Agonist activity on human recombinant TRPV1-mediated enhancement of intracellular calcium concentration in HEK293 cellsMore data for this Ligand-Target Pair
Affinity DataKi: 43nMAssay Description:The following fluorescent ligand displacement assays at 24 °C were used to further confirm and/or determine if the cytosolic lipidic ligand "chaperon...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nM ΔG°: -8.26kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Binding affinity to human recombinant CB1 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nM ΔG°: >-6.93kcal/molepH: 7.4 T: 2°CAssay Description:IC50 values for test compounds were determined from nonlinear regression analysis of data collected from ligand displacement experiments. The inhibit...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Tested for binding affinity to Cannabinoid receptor 1More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Binding affinity to human recombinant CB2 receptor expressed in COS cellsMore data for this Ligand-Target Pair
Affinity DataKi: 2.00E+4nMAssay Description:Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the presence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H...More data for this Ligand-Target Pair
Affinity DataKi: 3.10E+4nMAssay Description:Binding affinity towards Cannabinoid receptor 2 from mouse spleen membranes using 0.8 nM [3H]CP-55940 as radioligandMore data for this Ligand-Target Pair
Affinity DataKi: 4.40E+4nMAssay Description:Binding affinity towards cannabinoid receptor 1 from rat forebrain membranes in the absence of phenylmethanesulfonylfluoride (PMSF) using 0.8 nM [3H]...More data for this Ligand-Target Pair
Affinity DataKi: 5.00E+5nMAssay Description:Inhibition of acid ceramidase (unknown origin)More data for this Ligand-Target Pair