BDBM294303 US9586948, Example 22

SMILES Cn1cc(NC(=O)c2cccc(n2)-c2ccsc2)c(n1)C(N)=O

InChI Key InChIKey=SGPNWUYYNYULHU-UHFFFAOYSA-N

Data  3 IC50

Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 294303   

TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM294303(US9586948, Example 22)
Show SMILES Cn1cc(NC(=O)c2cccc(n2)-c2ccsc2)c(n1)C(N)=O
Show InChI InChI=1S/C15H13N5O2S/c1-20-7-12(13(19-20)14(16)21)18-15(22)11-4-2-3-10(17-11)9-5-6-23-8-9/h2-8H,1H3,(H2,16,21)(H,18,22)
Affinity DataIC50: 401nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
TargetInterleukin-1 receptor-associated kinase 4(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM294303(US9586948, Example 22)
Show SMILES Cn1cc(NC(=O)c2cccc(n2)-c2ccsc2)c(n1)C(N)=O
Show InChI InChI=1S/C15H13N5O2S/c1-20-7-12(13(19-20)14(16)21)18-15(22)11-4-2-3-10(17-11)9-5-6-23-8-9/h2-8H,1H3,(H2,16,21)(H,18,22)
Affinity DataIC50: 401nMAssay Description:Inhibition of human recombinant N-terminal GST-tagged full-length IRAK4 expressed in baculovirus infected Sf9 insect cells using 5FAM-RKRQGSVRRRVH-CO...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid