BDBM29502 Pyrazolo[1,5-a]-1,3,5-triazine, 13-27

SMILES CCCN(C)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)nc1C

InChI Key InChIKey=DIKAKISKKJNCKD-UHFFFAOYSA-N

Data  1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 29502   

TargetCorticotropin-releasing factor receptor 1(Rattus norvegicus (rat))
Bristol-Myers Squibb Co.

LigandPNGBDBM29502(Pyrazolo[1,5-a]-1,3,5-triazine, 13-27)
Show SMILES CCCN(C)c1nc(C)nc2c(c(C)nn12)-c1ccc(OC)nc1C
Show InChI InChI=1S/C18H24N6O/c1-7-10-23(5)18-21-13(4)20-17-16(12(3)22-24(17)18)14-8-9-15(25-6)19-11(14)2/h8-9H,7,10H2,1-6H3
Affinity DataIC50: 17.6nMpH: 7.2 T: 2°CAssay Description:Naive rats were sacrificed by decapitation, and the brain and pituitary were collected. Slide-mounted brain sections were preincubated in an assay so...More data for this Ligand-Target Pair