BDBM312517 2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,2-b]pyridazine-6-carboxamide::US9604989, Example 5

SMILES NC(=O)c1ccc2nc(c(-c3ccccc3)n2n1)-c1ccc(cc1)C1(N)CCC1

InChI Key InChIKey=JBGYKRAZYDNCNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 312517   

TargetRAC-beta serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM312517(2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,...)
Affinity DataIC50:  18nMAssay Description:His-tagged human recombinant kinase full-length Akt2 expressed in insect cells and activated by PDK1 was purchased form Invitrogen (part number PV 39...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetRAC-alpha serine/threonine-protein kinase(Homo sapiens (Human))
Bayer Intellectual Property

US Patent
LigandPNGBDBM312517(2-[4-(1-Aminocyclobutyl)phenyl]-3-phenylimidazo[1,...)
Affinity DataIC50:  5.20nMAssay Description:For the assay 50 nl of a 100 fold concentrated solution of the test compound in DMSO was pipetted into a black low volume 384 well microtiter plate (...More data for this Ligand-Target Pair
In DepthDetails US Patent