BDBM31768 CHEMBL295698::Ketoconazole::Nizoral::Panfungol
SMILES CC(=O)N1CCN(CC1)c1ccc(OC[C@@H]2CO[C@](Cn3ccnc3)(O2)c2ccc(Cl)cc2Cl)cc1
InChI Key InChIKey=XMAYWYJOQHXEEK-ZEQKJWHPSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 31768
Affinity DataKi: 398nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 400nMAssay Description:Inhibition of human recombinant aromatase assessed as conversion of O-dibenzylfluorescein benzyl ester substrate to fluorescein byproduct by fluorome...More data for this Ligand-Target Pair
Affinity DataKi: 6.50E+4nMAssay Description:Binding affinity was measured on Cytochrome P450 19A1More data for this Ligand-Target Pair
Affinity DataIC50: 3.96E+4nMAssay Description:Inhibition of cytochrome P450 19A1 involved in steroid biosynthesisMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of CYP19 (unknown origin) using O-benzyl fluorescein benzyl ester substrate preincubated for 10 mins by fluorimetric analysis relative to ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of CYP19More data for this Ligand-Target Pair
Affinity DataIC50: 900nMAssay Description:Inhibition of human recombinant aromataseMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human recombinant aromatase expressed in baculovirus/insect cells using 7-methoxy-trifluoromethylcoumarin as substrate after 30 mins by...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Cytochrome P450 19A1 in Human placental microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human aromatase by fluorometric assayMore data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant aromataseMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of human placental microsome CYP19More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:Inhibition of CYP19 in human placental microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Cyp19 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of progesterone 6-beta-hydroxylase in rat hepatic microsomesMore data for this Ligand-Target Pair