BDBM320690 (R)- or (S)-6-(Dimethylamino)-1-(1- (3-fluoro-4-(2,2,2- trifluoroethyl)phenyl)propyl)-3- (hydroxymethyl)-1H-pyrazolo[3,4- d]pyrimidin-4(5H)-one::US10174037, Example 96::US10174037, Example 97
SMILES CCC(c1ccc(CC(F)(F)F)c(F)c1)n1nc(CO)c2c1nc([nH]c2=O)N(C)C
InChI Key
Data 4 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 320690
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.0900nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
Affinity DataKi: 0.110nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.320nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Performed by Lab B. The activity of the compounds in accordance with the present invention as PDE2 inhibitors may be readily determined using a fluor...More data for this Ligand-Target Pair