BDBM321115 (S)-methyl (8-((2-amino-2,4-dimethylpentyl)oxy)-9-fluoro-6H-isochromeno[3,4-c]pyridin-2-yl)carbamate::US10174044, Example 49

SMILES COC(=O)Nc1cc-2c(OCc3cc(OC[C@@](C)(N)CC(C)C)c(F)cc-23)cn1

InChI Key InChIKey=NFTBUSBDGVMBKA-NRFANRHFSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 321115   

TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb

US Patent
LigandPNGBDBM321115((S)-methyl (8-((2-amino-2,4-dimethylpentyl)oxy)-9-...)
Affinity DataIC50:  5.40nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent